Late Recurrences of Cushing’s Disease after Initial Successful Transsphenoidal Surgery
نویسندگان
چکیده
منابع مشابه
Pituitary Surgery for Cushings Disease
In this article, the present status of neurosurgical operations for Cushing’s disease is briefly reviewed. Transsphenoidal surgery is considered the treatment of choice in most patients with Cushing’s disease once the diagnosis has been established. In a considerable proportion of patients, even sophisticated imaging does not directly depict the tiny micro adenoma. The search for the tumor is t...
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BACKGROUND Transsphenoidal surgery (TSS) is the treatment of choice for Cushing's disease (CD). Postoperative hypercortisolemia mandates further therapy. OBJECTIVE The aim of the study was to characterize patients without immediate postoperative remission who have a delayed decrease to normal or low cortisol levels without further therapy. DESIGN AND SETTING A retrospective case series was ...
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In eight hyperprolactinemic amenorrheic women who had a microprolactinoma, LH secretion was examined by measuring its concentration in blood samples collected every 15 min for 6 h before and 8 days after successful selective adenomectomy. Computer analysis was used for LH peak evaluation. In both circumstances, serum PRL and basal estradiol (E2) levels were also determined. Before operation, th...
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BACKGROUND Olfaction has been demonstrated to have a great impact on patients' lives. Transsphenoidal endoscopic pituitary surgery is associated with potentially significant damage to olfactory tissues, but to date this issue has been only poorly documented in the literature. STUDY DESIGN Prospective cohort study comparing olfactory outcomes pre- and postpituitary surgery. METHOD Patients w...
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To evaluate possible risk factors for meningitis, we retrospectively reviewed 228 transsphenoidal operations (in which a standard regimen of amoxicillin prophylaxis was used) for sellar pathology. The incidence of meningitis was 3.1% (seven of 228 cases). Cultures of preoperative specimens from the anterior nasal vestibule in three of seven patients yielded Staphylococcus aureus, but none of th...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2008
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2007-2013